an empty area (usually bounded in some way between things)(noun.shape)
Example: The architect left space in front of the building.
They stopped at an open space in the jungle.
The space between his teeth.
source: wordnet30
an area reserved for some particular purpose(noun.location)
Example: The laboratory's floor space.
source: wordnet30
any location outside the Earth's atmosphere(noun.location)
Example: The astronauts walked in outer space without a tether.
The first major milestone in space exploration was in 1957, when the USSR's Sputnik 1 orbited the Earth.